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🩸 Paid Sickle Cell Disease Clinical Trials

Browse recruiting sickle cell disease clinical trials across the United States. Find eligibility information, locations and research opportunities near you.

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Sickle Cell Disease
Condition

Active Clinical Trials for Sickle Cell Disease

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Disclaimer: This content is for educational purposes and is not medical advice. Always consult a qualified healthcare provider for medical guidance.

About Sickle Cell Disease

Sickle cell disease is an inherited blood disorder where red blood cells become crescent-shaped, causing severe pain and complications. Clinical trials investigate gene therapies, disease-modifying agents, and treatments for acute complications like vaso-occlusive crises.

Common Symptoms

Severe pain episodes (crises), anemia, fatigue, swelling of hands and feet, frequent infections, delayed growth, vision problems, jaundice, stroke risk

Risk Factors

Family history, African ancestry, Mediterranean, Middle Eastern, or Indian ancestry, inheritance of two sickle cell genes (HbSS)

Treatment Overview

Treatment includes hydroxyurea to reduce crisis frequency, blood transfusions, pain management, and bone marrow transplant. Clinical trials explore CRISPR-based gene editing, gene addition therapies, and novel anti-sickling agents including voxelotor and crizanlizumab.

Why Participate?

Sickle cell disease clinical trials are transforming treatment with gene therapies and disease-modifying agents that offer potential cures.

Related Conditions

States with Sickle Cell Disease Clinical Trials

Cities with Sickle Cell Disease Clinical Trials

Frequently Asked Questions About Sickle Cell Disease Clinical Trials

Sickle cell disease clinical trials test gene therapies, disease-modifying medications, and treatments for acute pain crises. Studies are exploring potentially curative approaches using CRISPR and other gene editing technologies.
Eligibility depends on genotype (HbSS, HbSC, etc.), crisis frequency, disease complications, and prior treatments. Gene therapy studies often require certain age ranges.
Compensation varies. Participants may receive $75-$200 per visit with comprehensive medical monitoring provided at no cost.
Yes, participants receive close medical monitoring throughout the study. All trials have independent safety committees and ethical oversight.